Acular LS

ACULAR LS® ophthalmic solution is a non-steroidal anti-inflammatory (NSAID) indicated to reduce ocular pain, burning and stinging. Acular LS has active ingredients of ketorolac tromethamine. While it was originally used for pain following refractive eye surgery, it is commonly used for other eye inflammations, eye irritation, eyelid pain, seasonal allergic conjunctivitis, and prevention of postoperative ocular inflammation after cataract extraction .

How we use this drug:  We use Acular LS to quiet inflammation of the eye and eyelids.  In general, because it is less potent than a steroid, it is associated with fewer side effects and works well for mild chronic inflammations.

Supplied: 5 mL in 10 mL bottle

Dose:

  • For most ocular inflammation:

one drop four times a day

  • Indicated to reduce ocular pain and burning/stinging following corneal refractive surgery

Instill 1 gtt in the operated eye PRN for up to 4 days postoperatively

  • Prevention of postoperatvie cystoid macular edema:

1-2 gtt in affected eye(s) q6-8hr beginning 24 hr pre-op and continuing 3-4 wk postoperatively

Children: Safety and effectiveness of Acular LS in pediatric patients below the age of 3 have not been established.

Pregnancy: (Category C) There are no adequate and well-controlled studies in pregnant women. ACULAR LS® ophthalmic solution should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Side Effects:

The most frequently reported adverse reactions occurring in approximately 1 to 5 percent of the study population were:

  • conjunctival hyperemia
  • corneal infiltrates
  • headache
  • ocular edema
  • ocular pain.

Other side effects include:

  • delayed wound healing
  • keratitis
  • And in some susceptible patients, continued use of topical NSAIDs may result in epithelial breakdown, corneal thinning, corneal erosion, corneal ulceration or corneal perforation
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