Ceftin (cefuroxime)

This drug is a second-generation cephalosporin with good efficacy against common ocular pathogens.  It is distinctly different from other cephalopsporins making it highly unlikely to result in a reaction in a person with true (i.e., authenticated) penicillin allergy.  Ceftin (cefuroxime) is used to treat a wide variety of bacterial infections.

Dose: dosed at 500mg b.i.d. for one week.  Take this medication by mouth usually twice daily, or as directed. Take cefuroxime with food to increase absorption and reduce stomach upset.

Supplied: Tabs—20, 60; Susp 125mg/5mL—100mL; Susp 250mg/5mL—50mL, 100mL

How we use this drug: Typically, we use Augmentin to treat bacterial infections of the eyelids.

Comment:  Cephalosporins are first-line treatment for many infections and are used widely in eye care.  More than 90% of patients who report a history of penicillin allergy lack penicillinspecific IgE and can tolerate the antibiotic safely.  Penicillin allergy should not prevent the use of second- and third-generation cephalosporins with distinct side-chains.  These are cefuroxime, cefprozil, ceftazidine and cefpodoxime.

Side Effects: Nausea, vomiting, diarrhea, or stomach pain may occur.  Dizziness and drowsiness may occur less frequently, especially with higher doses. If any of these effects persist or worsen, notify our office.

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