Septra is an antibiotic combination containing sulfamethoxazole and trimethoprim and it works by killing sensitive bacteria. Sulfamethoxazole and trimethoprim are both antibiotics that treat different types of infection caused by bacteria.
In true penicillin-allergic patients, Septra DS is an option.
Supplied: Tablets: 160 mg trimethoprim and 800 mg sulfamethoxazole (Septra DS); 80 mg trimethoprim and 400 mg sulfamethoxazole (Septra).
Dose: 1-2 DS tablets PO q12-24hr
Drink plenty of fluids to prevent kidney stones while you are taking trimethoprim and sulfamethoxazole.
Children: Contraindicated in pediatric patients less than 2 months of age.
Pregnancy: (Category C) Because trimethoprim and sulfamethoxazole may interfere with folic acid metabolism, Septra should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Side Effects: Sulfamethoxazole/trimethoprim may cause dizziness, headache, lethargy, diarrhea, anorexia, nausea, vomiting and rash.
Warnings: Diarrhea is a common problem caused by antibiotics which usually ends when the antibiotic is discontinued. Sometimes after starting treatment with antibiotics, patients can develop watery and bloody stools (with or without stomach cramps and fever) even as late as two or more months after having taken the last dose of the antibiotic. If this occurs, patients should contact their physician as soon as possible