Cosopt is used to treat certain types of glaucoma and other causes of high pressure inside the eye.

Cosopt eye drops contain a combination of dorzolamide and timolol. Dorzolamide reduces the amount of fluid in the eye, which decreases pressure inside the eye. Timolol is a beta-blocker that also reduces pressure inside the eye.

Supplied: 10 mL in an 18 mL

Dose:  The dose is one drop of Cosopt in the affected eye(s) two times daily.

If more than one topical ophthalmic drug is being used, the drugs should be administered at least ten minutes apart.

Children: Safety and efficacy in pediatric patients below the age of 2 years have not been established.

Pregnancy: (Category C) There are no adequate and well-controlled studies in pregnant women. Cosopt should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Side Effects:

Side Effects:  Get emergency medical help if you have any of these signs of an allergic reaction to Cosopt: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Although the risk of serious side effects is low when dorzolamide and timolol is used in the eyes, you should be aware of side effects that can occur if the medication is absorbed into your bloodstream.

Stop using dorzolamide ophthalmic and call your doctor at once if you have a serious side effect such as:

  • swelling or redness of your eyelids;
  • eye redness, pain, discomfort, or sensitivity to light;
  • drainage, crusting, or oozing of your eyes or eyelids;
  • wheezing, gasping, or other breathing problems;
  • swelling, rapid weight gain;
  • feeling short of breath, even with mild exertion; or
  • severe skin reaction: fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

Warnings:  Cosopt is contraindicated in patients with:

  • reactive airway disease;
  • bronchial asthma;
  • a history of bronchial asthma;
  • severe chronic obstructive pulmonary disease
  • sinus bradycardia;
  • sino-atrial block;
  • second or third degree atrioventricular block;
  • overt cardiac failure
  • cardiogenic shock; or
  • hypersensitivity to any component of this product.

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